سبتمبر 19th, 2018

 

acetazolamide

acetazolamide an inhibitor of carbonic anhydrase that is useful as a diuretic. It acts by preventing bicarbonate reabsorption in the proximal tubules of the kidney.

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acetate–CoA ligase

acetate–CoA ligase EC 6.2.1.1; systematic name: acetate:CoA ligase (AMP-forming); other names: acetyl–CoA synthetase; acyl-activating enzyme; acetate thiokinase; acetyl-activating enzyme. An enzyme that catalyses a reaction between ATP, acetate, and CoA to form AMP, pyrophosphate, and acetyl-CoA. It is an important enzyme in organisms (e.g. Escherichia coli, many fungi, protozoans, algae) that utilize acetate as a carbon source. Distinguish from acetate– CoA ligase (ADP-forming), EC 6.2.1.13.

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acetaminophen

acetaminophen or paracetamol 4-acetamidophenol; N-acetyl-paminophenol; N-(4-hydroxyphenyl)acetamide; a drug widely used as an analgesic and antipyretic. It inhibits formation of prostaglandins within, but not outside the brain. It is metabolized within the liver mostly to glucuronide and sulfate conjugates. A small amount is oxidized to a highly reactive intermediate, Nacetylbenzoquinoneimine, that is normally detoxified by conjugation with glutathione. If it is produced in excess of the capacity of the…

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acesulfame

acesulfame 6-methyl-1,2,3-oxathiazin-4(3H)-one 2,2′-dioxide; a sweet-tasting material that, as the potassium salt, has been used in foods and cosmetics.

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Aces

Aces abbreviation for N-(2-acetamido)-2-aminoethane sulfonic acid; 2-ethane sulfonic acid; a Good buffer substance, pKa (20°C) = 6.9.

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aceruloplasminemia

aceruloplasminemia or acaeruloplasminaemia a rare autosomal recessive disorder in which plasma ceruloplasmin is severely deficient, characterized by neurological abnormalities and systemic hemosiderosis. Any of at least six mutations in a locus at 3q21-q24 can cause the disease.

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